Pathfinder autonomous rendezvous and docking project

Capabilities are being developed and demonstrated to support manned and unmanned vehicle operations in lunar and planetary orbits. In this initial phase, primary emphasis is placed on definition of the system requirements for candidate Pathfinder mission applications and correlation of these system-level requirements with specific requirements. The FY-89 activities detailed are best characterized as foundation building. The majority of the efforts were dedicated to assessing the current state of the art, identifying desired elaborations and expansions to this level of development and charting a course that will realize the desired objectives in the future. Efforts are detailed across all work packages in developing those requirements and tools needed to test, refine, and validate basic autonomous rendezvous and docking elements

Prospectus, October 12, 1973

AGNEW RESIGNS VICE-PRESIDENCY; Small Turnout For Election; Prospectus Editors Announced; Walk Attracts Over 600; All Amendments Pass; Prospectus In Perspective: Excellent Bike Path Choice, Letters From Our Readers, New Magazine Coming, At this point in time.....; The Short Circuit; Drama Department Introduces New Lounge Theatre; United Way Campaign Begins; Announces $19,290 Bog Award; Ieardi Headlines Talent Program; Road Rally Club; New Breed of Businessman: Young College Graduate; Student Appointed As Board Member; New Concept For P/C Typing Classes; New Name, Faces For Magazine; Parkland Team To Debate At Bradley Oct. 20; Parkland Instructor Hospitalized at Mercy; PCA Appoints Student Affairs Committee Members; C-U Politics To Be Discussed At Forum; Walk For Mankind; Parkland Announces Bike Rules; Student Senate Reviews Charters, Future Plans; Gayle Wright Chosen To Advise Capstone; Vet\u27s Outreach Aids Readjustment; Prospectus Gains Two Campus Cartoonists; Seminar Planned On \u27Volunteering\u27; P/C Biologists At IACCB Convention; \u27Siege\u27 Shocking, Relevant Film; Faculty Members To Hold Offices; Winter Registration Information; Parkland Student Wins Santa Fe Scholarship; Birthday Wishes; Pre-Registration Benefits All; Target Program To Sponsor Open House; Women Voters Begin Sale Of ERA Bracelet; Ferlinghetti Sues San Francisco Police; Applications Must Be Filed; A Column By And For Women: Born To Be A Woman, The Way It Used To Be, The Lib, I Am Woman; Mutt and Mortie; Fast Freddy\u27s Football Forecast; Fall Intramural; Bowling Bulletin Board; Football Results; Dennis Bailen Wins Fast Freddy; Monday\u27s Coach; Rugby Play Not Football; Harriers Slump To Third, Fourth; Hiser Receives Babe Ruth Award; Graduation; TARGET Sets Sights On Juveniles; Classified Ads; Johnson Calls For Truth, Integrity; Gammon: \u27Everyone Born With Ability\u27; Student President\u27s Report; Lives Changed By Jesus Christ; Cruisin\u27 \u2773; Candidates Learn Voting Procedure; Speleunkers Travel Virgin Paths; Krannert Art Center Schedule; Illini Student Union Movies; Lab Develops Self-Study Habits; Callboard; Race To Fund Town With Doctor; Council Member Proposes Later Bar Hourshttps://spark.parkland.edu/prospectus_1973/1004/thumbnail.jp

It Is Time To Take A Stand For Medical Research And Against Terrorism Targeting Medical Scientists

Terrorists are attacking scientists who are attempting to alleviate human suffering. We need a concerted public effort to eliminate these acts, particularly the harassment of scientists studying nonhuman primates. This need is highlighted by the attacks upon the home of our friend and colleague, the noted medical scientist, Dr. Edythe London, professor of psychiatry and biobehavioral sciences and of molecular and medical pharmacology at the David Geffen School of Medicine at the University of California Los Angeles (UCLA). Her work exemplifies the unique role of research involving nonhuman primates in enabling the results of research in simple systems (oocytes, cell culture) and lower organisms to be applied to human diseases. The importance of Dr. London’s research was highlighted in a public letter issued on February 8, 2008 from the Director of the National Institutes of Health (NIH), Dr. Elias Zerhouni, who stated, “her work is a prime example of NIH’s efforts … to develop effective treatments for people suffering from addiction—a disease that devastates individuals, families, communities, and costs society more than half a trillion dollars annually in health and crime-related costs and losses in productivity.

Health-status outcomes with invasive or conservative care in coronary disease

BACKGROUND In the ISCHEMIA trial, an invasive strategy with angiographic assessment and revascularization did not reduce clinical events among patients with stable ischemic heart disease and moderate or severe ischemia. A secondary objective of the trial was to assess angina-related health status among these patients. METHODS We assessed angina-related symptoms, function, and quality of life with the Seattle Angina Questionnaire (SAQ) at randomization, at months 1.5, 3, and 6, and every 6 months thereafter in participants who had been randomly assigned to an invasive treatment strategy (2295 participants) or a conservative strategy (2322). Mixed-effects cumulative probability models within a Bayesian framework were used to estimate differences between the treatment groups. The primary outcome of this health-status analysis was the SAQ summary score (scores range from 0 to 100, with higher scores indicating better health status). All analyses were performed in the overall population and according to baseline angina frequency. RESULTS At baseline, 35% of patients reported having no angina in the previous month. SAQ summary scores increased in both treatment groups, with increases at 3, 12, and 36 months that were 4.1 points (95% credible interval, 3.2 to 5.0), 4.2 points (95% credible interval, 3.3 to 5.1), and 2.9 points (95% credible interval, 2.2 to 3.7) higher with the invasive strategy than with the conservative strategy. Differences were larger among participants who had more frequent angina at baseline (8.5 vs. 0.1 points at 3 months and 5.3 vs. 1.2 points at 36 months among participants with daily or weekly angina as compared with no angina). CONCLUSIONS In the overall trial population with moderate or severe ischemia, which included 35% of participants without angina at baseline, patients randomly assigned to the invasive strategy had greater improvement in angina-related health status than those assigned to the conservative strategy. The modest mean differences favoring the invasive strategy in the overall group reflected minimal differences among asymptomatic patients and larger differences among patients who had had angina at baseline

Initial invasive or conservative strategy for stable coronary disease

BACKGROUND Among patients with stable coronary disease and moderate or severe ischemia, whether clinical outcomes are better in those who receive an invasive intervention plus medical therapy than in those who receive medical therapy alone is uncertain. METHODS We randomly assigned 5179 patients with moderate or severe ischemia to an initial invasive strategy (angiography and revascularization when feasible) and medical therapy or to an initial conservative strategy of medical therapy alone and angiography if medical therapy failed. The primary outcome was a composite of death from cardiovascular causes, myocardial infarction, or hospitalization for unstable angina, heart failure, or resuscitated cardiac arrest. A key secondary outcome was death from cardiovascular causes or myocardial infarction. RESULTS Over a median of 3.2 years, 318 primary outcome events occurred in the invasive-strategy group and 352 occurred in the conservative-strategy group. At 6 months, the cumulative event rate was 5.3% in the invasive-strategy group and 3.4% in the conservative-strategy group (difference, 1.9 percentage points; 95% confidence interval [CI], 0.8 to 3.0); at 5 years, the cumulative event rate was 16.4% and 18.2%, respectively (difference, 121.8 percentage points; 95% CI, 124.7 to 1.0). Results were similar with respect to the key secondary outcome. The incidence of the primary outcome was sensitive to the definition of myocardial infarction; a secondary analysis yielded more procedural myocardial infarctions of uncertain clinical importance. There were 145 deaths in the invasive-strategy group and 144 deaths in the conservative-strategy group (hazard ratio, 1.05; 95% CI, 0.83 to 1.32). CONCLUSIONS Among patients with stable coronary disease and moderate or severe ischemia, we did not find evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of ischemic cardiovascular events or death from any cause over a median of 3.2 years. The trial findings were sensitive to the definition of myocardial infarction that was used